FDA approves Cara’s drug for severe itching in kidney disease patients

 Kidney disease, Cara's drug, Cara's drug for Kidney, Itching in Kidney, Korsuva, Kidney patients drug, FDA drug for kidney, world news

The company expects to commercially launch the injection, Korsuva, in the first quarter of 2022, Chief Executive Officer Derek Chalmers said in an interview. The drug is designed to be administered three times a week after each dialysis.

The Food and Drug Administration on Monday approved Cara Therapeutics’s drug to treat moderate-to-severe itching in patients with chronic kidney disease undergoing dialysis, making it the first therapy for the ailment in the United States.

The company expects to commercially launch the injection, Korsuva, in the first quarter of 2022, Chief Executive Officer Derek Chalmers said in an interview. The drug is designed to be administered three times a week after each dialysis.

It reduces the activity of the sensory nerve that relays itching from the skin to the spinal cord and subsequently to the brain.

Chronic kidney disease patients with severe itching currently take depressants such as barbiturates and allergy medication antihistamines.

Cara’s shares were unchanged after the bell, having gained about 4% in regular trading on Monday.

Top News Right Now

The company has an exclusive license agreement with Switzerland-based Vifor Pharma for Korsuva, under which it would earn 60% of the profit on U.S. sales.

Cara said it could price the drug similar to the $17,000 annual cost of Amgen Inc’s treatment Parsabiv, which treats secondary hyperparathyroidism, or excessive secretion of parathyroid hormone, in kidney disease patients.

Jefferies analyst Christopher Howerton estimates Korsuva will generate peak sales of about $900 million in 2030.

 

Comments

Post a Comment

Popular posts from this blog

Kabul airport attack kills 60 Afghans, 12 U.S. troops; IS claims responsibility

Image
  The Islamic State group claimed responsibility for the killings on its Amaq news channel Two suicide bombers and gunmen attacked crowds of Afghans flocking to Kabul's airport on Thursday, transforming a scene of desperation into one of horror in the waning days of an airlift for those fleeing the Taliban takeover. The attacks killed at least 60 Afghans and 12 U.S. troops, Afghan and U.S. officials said. The U.S. general overseeing the evacuation vowed the United States would “go after” the perpetrators of the bombings, and warned that more such attacks are expected. “We are working very hard right now to determine attribution, to determine who is associated with this cowardly attack. And we’re prepared to take action against them,” Gen. Frank McKenzie, head of U.S. Central Command, told Pentagon reporters in a briefing. “Twenty-four-seven. We are looking for them.” Shortly after Gen. McKenzie spoke, the Islamic State group claimed responsibility for the killings...
Read more

Kabul Blasts: "Voice Cracking", Biden Reflected Blow To His Presidency

Image
  Kabul Airport Attack: No doubt that Joe Biden's presidency has been shaken to the core by the bombing at Kabul's airport. Washington, United States: Eyes closing, voice cracking, Joe Biden physically reflected the terrible blow to his presidency from the slaying of 13 US service members during the desperate Kabul evacuation. Addressing the nation from the White House, Biden bowed his head for a moment of silence before taking questions from journalists pressing him on the bloody twist in the already tragic operation to shut down the 20-year war in Afghanistan. He appeared occasionally close to tears as he spoke of the dead "heroes." And when he promised the attackers "we will hunt you down," there was steel in his voice. No doubt that Biden's presidency has been shaken to the core by the bombing at Kabul's airport. In January, he took office promising calm at home and respect for the United States abroad after the turbulent Donald Trump...
Read more

Britain To End Afghanistan Evacuations In "Matter Of Hours"

Image
  "We will process those people that we have brought with us, the 1,000 people approximately inside the airfield now," British Defence Secretary Ben Wallace told Sky News. London, United Kingdom: Britain said Friday that it plans to complete its evacuations out of Afghanistan "in a matter of hours". "We will process those people that we have brought with us, the 1,000 people approximately inside the airfield now," British Defence Secretary Ben Wallace told Sky News. "And we will seek a way to continue to find a few people in the crowd, where we can, but overall the main processing has now closed and we have a matter of hours." Wallace said that the UK had "closed the Baron Hotel" at 0330 GMT, where those wanting to fly to Britain had gathered. It also closed the processing centre for asylum seekers, and shut Abbey Gate, one of the points of access to Kabul airport and one of the areas targeted in the twin suicide bombings on T...
Read more